Library
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Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
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This handout discusses muscular dystrophy (MD), primarily in dogs. The cause of the disease is a defect in the proteins found in muscle cells. It is often an inherited disease, usually affecting young dogs. Clinical signs (usually starting as muscle weakness) and diagnosis of the condition are outlined. There is no effective treatment for the condition.
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Myasthenia gravis is a disease in which there is a malfunction in the transmission of signals between the nerves and muscles. Dogs with myasthenia gravis exhibit extreme weakness and excessive fatigue. There are two forms: inherited and acquired. Anti-acetylcholinesterase medication and immunosuppressive therapy will likely be required for the life of the dog.
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A narcoleptic episode involves sudden collapse and loss of movement in which the pet literally falls asleep, often while physically active, then wakes up abruptly and proceeds as if nothing happened. Although you may not be able to stop the episodes, you may be able to reduce the frequency and severity of events by identifying possible patterns that precipitate the incidents.
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Navicular 'disease' is really a group of related conditions affecting the navicular bone and associated structures in the foot. There are several possible causes of pain in and around the navicular bone.
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Nose Bleeds (Epistaxis) in dogs can be extremely unsettling for the pet owner. Most acute (sudden) nosebleeds are caused by simple trauma or by upper respiratory tract infections. This handout discusses nosebleeds in dogs, the various causes of this condition, first aid recommendations and possible testing to find the root cause of the problem.
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A nutraceutical is a food or food product that reportedly provides health and medical benefits. Specific nutraceuticals are commonly used in the management of osteoarthritis in dogs. Because nutraceuticals are not subjected to the same testing and regulation as pharmaceuticals, it is always best to consult your veterinarian before giving any to your dog.
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Nutritional changes can improve the management and treatment of pancreatic diseases in dogs. To prevent chronic pancreatitis relapses, diet adjustments will be necessary. Diet factors for managing exocrine pancreatic insufficiency, diabetes mellitus, pancreatitis, and insulinoma are discussed. Recommendations for feeding diabetic dogs and approaching hypoglycemia are also described.
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Colitis is a fairly common problem in dogs manifesting as diarrhea. Dealing with colitis may boil down to working with your veterinarian to find a nutrient profile that allows your dog's gastrointestinal system to function as normally as possible. A nutrient profile which contains a high quality, high digestibility protein, low to moderate fat content, and high digestibility carbohydrates. Fiber may also play a role to benefit the colon of dogs with chronic colitis. Work with your veterinarian to assess your dog's clinical and nutritional history, create a nutritional plan, and then evaluate the success of the plan.